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POLG-related disorders should be suspected in patients with a family history or suggestive symptoms of a POLG-related disorder, including but not limited to unexplained encephalopathy, refractory epilepsy (focal, myoclonic), status epilepticus at presentation, developmental delays, psychomotor regression, axonal sensorimotor neuropathy, myopathy cerebellar ataxia, ophthalmoplegia, or complicated migraine with occipital aura

FSP1 is also an alternative suppressor of ferroptosis

Method to enhance delivery of glutathione and atp levels in cells

Liu Z, Zhang Y, Jin T, Yi C, Ocansey DK, Mao F

(accessed August 20, 2024)

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